From a licensing standpoint, Pennsylvania is as moderated and even-keeled as its founders. Although the Commonwealth regulates a number of industries, it doesn't go as far as many states. Even better, it keeps its forms and processes relatively simple and clear. Businesses in what was once known as America's Breadbasket won't find their hands tied when trying to establish themselves.
In Pennsylvania, retail businesses of all sorts including toy stores, clothing shops, photography businesses and general merchandisers need licenses and permits. In most cases, retail businesses take relatively few licenses – however being registered for all state and local taxes is important as is having any needed general business licenses.